The Status of Diabetes and Its Complications in Latin-American Population: A Review Article Diabetes Res Clin Pract. Jun 17; doi: /blogger.coms Online ahead of print. Authors Ricardo Correa 1 Author: Ricardo Correa, Sri Harsha Tella, Ghada Elshimy, Jaime A. Davidson Review article: drug hepatotoxicity Aliment Pharmacol Ther. May 15;25(10) doi: /jx. Authors C Y Chang 1, T Cited by: We review the evidence that strongly suggests a role of the intestinal microbiota in the onset and perpetuation of inflammatory bowel disease (IBD). Experimental studies consisted of suppressing micro-organisms from the microbiota (using germ-free or gnotoxenic animals or antibiotics), introducing n Review article: the role of bacteria in onset and perpetuation of inflammatory bowel Cited by:
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Observations: GERD can influence patients' health-related quality of life and is associated with an increased risk of esophagitis, esophageal strictures, Barrett esophagus, and esophageal review article pubmed. Obesity, tobacco smoking, and genetic predisposition increase the risk of developing GERD. Typical GERD symptoms are often sufficient to determine the diagnosis, but less common symptoms and signs, such as dysphagia and chronic cough, may occur.
Patients with typical GERD symptoms can be medicated empirically with a proton pump inhibitor PPI, review article pubmed. Among patients who do not respond to such treatment or if the diagnosis is unclear, endoscopy, esophageal manometry, and esophageal pH monitoring are recommended.
Patients with GERD symptoms combined with warning symptoms of malignancy eg, dysphagia, weight loss, bleeding and those with other main risk factors for esophageal adenocarcinoma, such as older age, male sex, and obesity, should undergo endoscopy. Lifestyle changes, medication, and surgery are the main treatment options for GERD. Weight loss and smoking cessation are often useful.
Medication with a PPI is the most common treatment, and after initial full-dose therapy, which usually is omeprazole 20 mg once daily, the aim is to use the lowest effective dose. Observational studies have suggested several adverse effects after long-term PPI, but these findings need to be confirmed before influencing clinical decision making.
Surgery with laparoscopic fundoplication is review article pubmed invasive treatment alternative in select patients after thorough and objective assessments, particularly if they are young and healthy. Endoscopic and less review article pubmed surgical techniques are emerging, which may reduce the use of long-term PPI and fundoplication, but the long-term safety and efficacy remain to be scientifically established. Conclusions and relevance: The clinical management of GERD influences the lives of many individuals and is responsible for substantial consumption of health care and societal resources, review article pubmed.
Treatments include lifestyle modification, PPI medication, and laparoscopic fundoplication. New endoscopic and less invasive surgical procedures are evolving. PPI use remains the dominant treatment, review article pubmed, but long-term therapy requires follow-up and reevaluation for potential adverse effects. Publication types Research Support, Non-U. Gov't Review. Substances Proton Pump Inhibitors Omeprazole.
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, time: 17:14Review article: the role of bacteria in onset and perpetuation of inflammatory bowel disease
PMID: Free PMC article. Review. Superior mesenteric artery stenting using embolic protection device for treatment of acute or chronic mesenteric ischemia. Mendes BC, Oderich GS, Tallarita T, Kanamori KS, Kalra M, DeMartino RR, Shuja F, Johnstone JK. Mendes BC, et al. J Vasc Surg. Oct;68(4) doi: /blogger.com Epub Apr J Vasc Surg. PMID Cited by: 7 We review the evidence that strongly suggests a role of the intestinal microbiota in the onset and perpetuation of inflammatory bowel disease (IBD). Experimental studies consisted of suppressing micro-organisms from the microbiota (using germ-free or gnotoxenic animals or antibiotics), introducing n Review article: the role of bacteria in onset and perpetuation of inflammatory bowel Cited by: Greinacher A, Thiele T, Warkentin TE, Weisser K, Kyrle PA, Eichinger S. Greinacher A, et al. N Engl J Med. Apr 9. doi: /NEJMoa Online ahead of
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